Most of the damage was done by two Stetson players. Griffin Gilstrap scored one goal in the first half and one in the second.
Kevin Muntz added a pair of second half goals, scoring them within 2:45.
Freshman midfielder Tyler Burkhardt prevented the shutout when he scored on a penalty kick with 6:11 left to play.
Both teams were credited with 24 shots.
The Bisons held a slight 14-13 edge in shots on goal. Andre Santos had three shots on goal for the Bisons. Drew Longinotti added a pair.
Brent McGee started in goal for the Bisons and gave up two goals while making three saves. Patrick Walsh allowed three goals and made five saves.
The Bisons are 3-7-2, 0-2-1 in the A-Sun. Stetson is 8-1-1, 2-1-0 in the conference.
Sunday afternoon the Bisons are in Fort Myers, Fla., to face Florida Gulf Coast at 1 p.m.