The Lady Bisons lost 25-15, 25-18 and 25-23.
The Lady Bisons will have to quickly rebound to play Tulane at 4 p.m.
Purdue is 3-1. Lipscomb is 2-2.
“ As we have always talked about I truly believe in playing tough competition,” Lady Bisons coach Brandon Rosenthal said. “We have done that since day one and this weekend is no different.
“All three teams are very good and experienced. The fact that we have never played these programs is very exciting. Not to mention this is the first time that we will take on a Big Ten opponent.”
Purdue concentrated on Lipscomb middle blocker Alex Kelly who finished with only seven kills.
Rosenthal expected Purdue to be the toughest match of the tournament.
“Purdue is a very disciplined team with a good bit of height,” Rosenthal said. “Their middles are very active and their setter is very offensively minded. Being in the Big Ten, Purdue faces tough competition day in and day out.”
"We did a nice job of adjusting. We did a good job of fighting back too. It was tough. They were by far the most physical team we have played, even more so than California last season." Tulane is led by Izabela Grot with 30 kills in nine sets. The Green Wave is 0-3 heading into the tournament.
“Tulane poses a different type of challenge as they bring in a younger team with a lot of talent,” Rosenthal said. “There is no doubt that their talent level is very impressive and while the season is very young they are still working some of their team issues out.
“I like the way we are playing right now. The key to the match will be the team that can defensively raise the bar. Offensively, this match should be a high-powered affair.”